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Prenatal maternal psychosocial stress and offspring's asthma and allergic disease: a systematic review and meta-analysis.

Author
Abstract
:

Prenatal maternal stress may influence offspring's atopic risk through sustained cortisol secretion resulting from activation of the hypothalamic-pituitary-axis (HPA), leading to Th2-biased cell differentiation in the fetus. We undertook a systematic review and meta-analysis investigating the relationship between prenatal maternal psychosocial stress and risk of asthma and allergy in the offspring.

Year of Publication
:
2018
Journal
:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Date Published
:
2018
ISSN Number
:
0954-7894
URL
:
http://dx.doi.org/10.1111/cea.13091
DOI
:
10.1111/cea.13091
Short Title
:
Clin Exp Allergy
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