SIMVASTATIN PREVENTS VASCULAR COMPLICATIONS IN THE CHRONIC REACTIVE OXYGEN SPECIES MURINE MODEL OF SYSTEMIC SCLEROSIS.
| Author | |
|---|---|
| Abstract |
:
Systemic sclerosis (SSc) is characterized by vasculopathy and organ fibrosis. Although microvascular alterations are very well characterized, structural and functional abnormalities of large vessels are not well defined. Therefore, we evaluated the effect of simvastatin administration on aortic and small renal arteries thicknening, and on myofibroblasts differentation in a murine model of systemic sclerosis. |
| Year of Publication |
:
2016
|
| Journal |
:
Free radical research
|
| Number of Pages |
:
1-28
|
| Date Published |
:
2016
|
| ISSN Number |
:
1071-5762
|
| URL |
:
http://www.tandfonline.com/doi/full/10.3109/10715762.2016.1149171
|
| DOI |
:
10.3109/10715762.2016.1149171
|
| Short Title |
:
Free Radic Res
|
| Download citation |
