Association of fibroblast growth factor 21 with alcohol consumption and alcohol liver cirrhosis.

Author
:
J Wagner-Skacel
A Horvath
P Grande
J Wenninger
F Matzer
C Fazekas
S Mörkl
A Meinitzer
Stadlbauer V
Abstract
:

Fibroblast growth factor 21 (FGF21) is produced in the liver and binds to different complex receptor/coreceptor systems. Besides many other processes, FGF21 regulates the intake of simple sugars and alcohol. Increased levels of FGF21 decrease harmful alcohol intake in mice. To increase our understanding on the relationship between FGF21 and alcohol intake in humans, we aimed to measure FGF21 levels in patients with alcoholic liver cirrhosis (ALC) in comparison to patients with nonalcoholic liver cirrhosis (NALC) and healthy persons based on their present alcohol consumption.
Year of Publication
:
2020
Journal
:
Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater
Date Published
:
2020
ISSN Number
:
0948-6259
URL
:
https://dx.doi.org/10.1007/s40211-020-00380-8
DOI
:
10.1007/s40211-020-00380-8
Short Title
:
Neuropsychiatr
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