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Coplanar polychlorinated biphenyls impair glucose homeostasis in lean C57BL/6 mice and mitigate beneficial effects of weight loss on glucose homeostasis in obese mice.

Author
Abstract
:

Previous studies demonstrated that coplanar polychlorinated biphenyls (PCBs) promote proinflammatory gene expression in adipocytes. PCBs are highly lipophilic and accumulate in adipose tissue, a site of insulin resistance in persons with type 2 diabetes.

Year of Publication
:
2013
Journal
:
Environmental health perspectives
Volume
:
121
Issue
:
1
Number of Pages
:
105-10
ISSN Number
:
0091-6765
URL
:
https://ehp.niehs.nih.gov/doi/10.1289/ehp.1205421?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
DOI
:
10.1289/ehp.1205421
Short Title
:
Environ Health Perspect
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