Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats.
| Author | |
| Abstract |
:
Recent work has shown that the novel compound N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) may selectively block nicotinic acetylcholine receptors involved in regulating dopamine release. The current experiments examined the acute effect of bPiDDB on nicotine self-administration, sucrose-maintained responding, and nicotine-induced changes in acute and sensitized locomotor activity. |
| Year of Publication |
:
2006
|
| Journal |
:
Psychopharmacology
|
| Volume |
:
184
|
| Issue |
:
3-4
|
| Number of Pages |
:
426-34
|
| ISSN Number |
:
0033-3158
|
| URL |
:
https://doi.org/10.1007/s00213-005-0163-8
|
| DOI |
:
10.1007/s00213-005-0163-8
|
| Short Title |
:
Psychopharmacology (Berl)
|
| Download citation |
