Complement activation predicts adverse pregnancy outcome in patients with systemic lupus erythematosus and/or antiphospholipid antibodies.

Author
:
MY Kim
MM Guerra
E Kaplowitz
CA Laskin
M Petri
DW Branch
MD Lockshin
LR Sammaritano
JT Merrill
TF Porter
A Sawitzke
AM Lynch
JP Buyon
JE Salmon
Abstract
:

Studies in mouse models implicate complement activation as a causative factor in adverse pregnancy outcomes (APOs). We investigated whether activation of complement early in pregnancy predicts APOs in women with systemic lupus erythematosus (SLE) and/or antiphospholipid (aPL) antibodies.
Year of Publication
:
2018
Journal
:
Annals of the rheumatic diseases
Date Published
:
2018
ISSN Number
:
0003-4967
DOI
:
10.1136/annrheumdis-2017-212224
Short Title
:
Ann Rheum Dis
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