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Evolutionary selection of personalized melanoma cell/tissue dual-homing peptides for guiding bionanofibers to malignant tumors.

Author
Abstract
:

Both melanoma cells and tissues were allowed to interact with an identical pool of billions of human-safe phage nanofiber clones with each genetically displaying a unique 12-mer peptide at the tips, respectively, resulting in the discovery of bionanofibers displaying a melanoma cell/tissue dual-homing peptide for personalized targeted melanoma therapy.

Year of Publication
:
2018
Journal
:
Chemical communications (Cambridge, England)
Date Published
:
2018
ISSN Number
:
1359-7345
DOI
:
10.1039/c7cc09077c
Short Title
:
Chem Commun (Camb)
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