Dual Effect of Histidine on Polysorbate 20 Stability: Mechanistic Studies.
| Author | |
|---|---|
| Abstract |
:
L-Histidine (L-His) and polysorbate 20 (PS20) are two excipients frequently included in parenteral products to stabilize biotherapeutics. The objective of the current work was to investigate the impact of L-His on PS20 stability in aqueous solutions when subjected to forced oxidation and accelerated stability testing. |
| Year of Publication |
:
2018
|
| Journal |
:
Pharmaceutical research
|
| Volume |
:
35
|
| Issue |
:
2
|
| Number of Pages |
:
33
|
| Date Published |
:
2018
|
| ISSN Number |
:
0724-8741
|
| URL |
:
https://dx.doi.org/10.1007/s11095-017-2321-1
|
| DOI |
:
10.1007/s11095-017-2321-1
|
| Short Title |
:
Pharm Res
|
| Download citation |
