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C3 glomerulonephritis secondary to mutations in factors H and I: rapid recurrence in deceased donor kidney transplant effectively treated with eculizumab.

Author
Abstract
:

C3 glomerulonephritis (C3GN) is caused by alternate complement pathway over-activation. It frequently progresses to end-stage renal disease, recurs in two-thirds of transplants and in half of these cases progresses to allograft loss. There is currently no proven treatment for C3GN.

Year of Publication
:
2018
Journal
:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Date Published
:
2018
ISSN Number
:
0931-0509
URL
:
https://academic.oup.com/ndt/article-lookup/doi/10.1093/ndt/gfx369
DOI
:
10.1093/ndt/gfx369
Short Title
:
Nephrol Dial Transplant
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